Arita Dubņika

Name, Surname:                   Arita Dubņika
Scientific degree:                 Doctoral Degree in Engineering Sciences (Dr.sc.ing.)
e-mail:                                  arita.dubnika[at]rtu.lv
Language skills:                    

Latvian– mother tongue
English – fluently
Russian – moderate
German – basic

Education:    

2010 -2014 doctoral studies in Riga Technical University, faculty of Materials Science and Applied Chemistry, program " Chemical Engineering”.
2008-2010 master studies in University of Latvia, Faculty of Chemistry;
2004-2008 bachelor studies in University of Latvia, Faculty of Chemistry;

Working experience:            

since 2010 Riga Technical University, Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre, researcher.
2008-2010 Investment and Development Agency of Latvia, Export Promotion Division, project manager;
2006-2008 Investment and Development Agency of Latvia, Information Provision Division, senior expert;
2005-2007 University of Latvia, Faculty of Chemistry, The Chair of Physical Chemistry, laboratory assistant;

Working experience abroad:   

01.06.2015 – 31.05.2016. Biomaterials and Advanced Drug Delivery Laboratory, Stanford University, School of Medicine, USA
07.01.2013-02.02.2013 AO Foundation, AO Research Institute, Davos Platz, Switzerland. Short Term Scientific Mission „In vitro evaluation of human MSC behaviour on silver doped hydroxyapatite surfaces“  within the COST Action Nr. MP 1005.

Experience in project performance:

  1. PostDoctoral researcher/project leader at  Post-doctoral Research Aid Latvia for project "Drug and growth factor dual delivery from different biomaterial carriers for bone tissue engineering" (2018-2021).
  2. WP leader of Horizon2020 Teaming Phase 1 project “Baltic Biomaterials Centre of Excellence” GA763721 (2017-2018)
  3. MC Member form Latvia at COST Action CA15216 “European Network of Bioadhesion Expertise: Fundamental Knowledge to Inspire Advanced Bonding Technologies” 2016. – 2020.
  4. Head of RTU project Nr. No. ZP-2016/14 “Functionalized silver doped hydroxyapatite scaffolds for controlled simultaneous silver ion and drug delivery”. 2016.-2017.
  5. Performer at multidisciplinary project between Riga Technical University and Riga Stradins University “Multifunctional nanosized calcium phosphate/hyaluronic acid hydrogels for the treatment of osteoporotic bone fractures”. 2016.-2019.
  6. Performer at EuroNanoMed2 project „POsTURE“ - PhOtocrosslinked hydrogels for guided periodontal TissUe Regeneration. 2015.-2017.
  7. Performer at EuroNanoMed2 project „NANOFOROSTEO“ - Multifunctional injectable nano HAp composites for the treatment of osteoporotic bone fractures. 2014.-2016.
  8. Performer in National Research Program No. 2014.10-4/VPP-3/21 “MultIfunctional Materials and composItes, photonicS and nanotechnology (IMIS2)”, Project No. 4 “Nanomaterials and nanotechnologies for medical applications”, Subproject No. 4.1. 2014.-2017.
  9. Head of grant scheme “Activities of Swiss researchers in Latvia” subproject Nr.1.4-2/11520 “Lecture series and promotion of scientific cooperation on x-ray diffractometry and Rietveld method applications”. 2013.
  10. Performer in RTU project Nr. ZP-2012/24 “Evaluation of physical and antimicrobial properties of silver doped hydroxyapatite depending on the preparation method”. 2012.
  11. Performer in ESF project „ Multidisciplinary Research in Biomaterials Technology of New Scientist Group”, Nr. 2009/0201/1DP/1.1.1.2.0/09/APIA/VIAA/090. 2011 – 2012.
  12. Performer in National Research Program No. 7416. „Modern functional materials for micro and nano electronics, fotonics, biomedicine, and constructive composites as well as appropriate technologies” 4th project „Prospective Biomaterials and medical technologies”. 2010 – 2012.
  13. Performer/project administrator in Baltisch-Deutsche Hochschulkontor project “Evaluierung wissenschaftlicher Methoden zur umfangreichen Charakterisierung bio-keramischer Implantatmaterialien für deren Applikation” 2011.
  14. Performer in RTU project Nr. ZP-2010/25 „ Development of local drug delivery systems based on porous calcium phosphate bioceramic scaffolds “. 2011.

Grants and scholarships:

  1. In 2014 - European Social Fund scholarship within the project “Support for the implementation of doctoral studies at Riga Technical University - 2”.
  2. In 2012/2013 - European Social Fund scholarship within the project “Support for the implementation of doctoral studies at Riga Technical University”.
  3. In 2008 - JSC “Grindeks” scholarship for development of Master thesis.
  4. In 2006 and 2007 - JSC “Grindeks” scholarship for development of Bachelor thesis;

Additional Education:

  1. 8h seminar “Analysis of inorganic substances - Thermo Fisher Scientific”, Labochema Latvia, (2013).
  2. 2 day seminar “Thermo Fisher Scientific”, Labochema Latvija,(2011)
  3. 2 day seminar “Modern applications in electron microscopy”, UAB Vildoma, (2011).
  4. 16h training „International Marketing”, LIAA (2010).
  5. 24h training „ Cluster Development Course “. LIAA, (2009).
  6. 16h training „ Attractive and convincing – Strategy of today’s communication“, Academy of communications (2008).
  7. 40h training “Intensive course of English” Interlink School of English, UK (2003).

Academical work:

  1. Supervision of bachelor thesis Anta Krumina “Development and characterization of porous silk-hydroxyapatite scaffolds for bone regeneration”, defended in 2018.
  2. Supervision of bachelor thesis Marite Skrinda “Development and characterization of liposomes for controlled drug delivery”, defended in 2018.
  3. Supervision of bachelor thesis: Karina Egle “Development of bioadhesive biomaterials based on silk and hyaluronic acid”, defended in 2018.
  4. Supervision of Bachelor thesis: Daila Kliedere “Dexamethasone sodium phosphate delivery systems on the basis of calcium phosphate/hyaluronic acid hydrogels”, defended in 2017.
  5. Supervision of Bachelor thesis: Laine Paidere “Development of strontium and silver substituted calcium phosphates for preparation of porous scaffolds”, defended in 2014.
  6. Supervision of Bachelor thesis: Lidija Isajeva „ Determination of gentamicin release kinetics from microencapsulated drug delivery systems with UPLC”, defended in 2013.
  7. Consultation of Master thesis: Lāsma Poča „Modification of silver doped hydroxyapatite and its in vitro evaluation in simulated body fluids”, defended in 2013.
  8. Consultation of Master thesis: Anete Miglāne “Study of silver ion bioavailability in chemically synthesized silver doped hydroxyapatites”, defended in 2013.
  9. Consultation of Master thesis: Alīna Bondarevska „Preparation and characterization hydroxyapatite/dexamethasone composites”, defended in 2012.
  10. Supervision of Bachelor thesis: Marina Volkova „ Determination of silver content in synthesized hydroxylapatite”, defended in 2012.
  11. Supervision of Bachelor thesis: Anete Miglāne „ Synthesis of silver loaded hydroxyapatite for drug delivery systems”, defended in 2011.

Other activities:

  1. Since 2012 - Member of “Association of Latvian Young Scientists”.
  2. Since 2012 - Member of “Materials Research Society of Latvia”.

Monographs and book chapters:

D.Loca, A.Dubnika, V.Zalite, J.Locs, L.Berzina-Cimdina. Porous hydroxyapatite for drug delivery. Chapter content in the „Hydroxyapatite (HAp) for biomedical applications” (Edited by: Professor Michael Mucalo, University of Waikato, New Zealand, Woodhead publishing).

Publications and scientific papers:

  1. Development of local strontium ranelate delivery systems and long term in vitro drug release studies in osteogenic medium. Loca, D., Smirnova, A., Locs, J., Dubnika, A., Vecstaudza, J., Stipniece, L., Makarova, E. Dambrova, M. Scientific Reports. 2018, Vol. 8/1, DOI: 10.1038/s41598-018-35197-7.
  2. Cytokines as therapeutic agents and targets in heart disease. Dubnika A, Manoukian MAC, Mohammadi MR, Parekh MB, Gurjarpadhye AA, Inayathullah M, Dubniks V, Lakey JRT, Rajadas J. Cytokine & Growth Factor Reviews. 2018, 43, 54-68.
  3. G.Sahmenko, E.Namsone, K.Rubenis, A.Dubnika, G.Niparts. Effect of various additives and aeration on the properties of lightweight concrete. Key Engineering Materials, 2018, Vol. 762, pp. 351-355.
  4. M.R. Mohammadi, A. Nojoomi, M. Mozafari, A. Dubnika, M. Inayathullah, J. Rajadas. Nanomaterials engineering for drug delivery: A hybridization approach. Journal of Materials Chemistry B, 2017, 5 (22), 3995-4018.
  5. A. Dubnika, D.Loca, V.Rudovica, MB. Parekh, L. Berzina-Cimdina. Functionalized silver doped hydroxyapatite scaffolds for controlled simultaneous silver ion and drug delivery. Ceramics International, 2017, 43(4), 3698–3705.
  6. A. Dubnika, D. Loca, L. Berzina-Cimdina. Cross-linked dexamethasone sodium phosphate delivery systems based on silver doped hydroxyapatite scaffolds, Key Engineering Materials, 2016, Vol. 721, pp. 192-196.
  7. Parekh MB, Gurjarpadhye AA, Manoukian MAC, Dubnika A, Rajadas J, Inayathullah M. Recent developments in diffusion tensor imaging of brain. Radiol Open J. 2015; 1(1): 1-12.
  8. AA. Gurjarpadhye, MB. Parekh, A. Dubnika, J. Rajadas and M. Inayathullah. Infrared Imaging Tools for Diagnostic Applications in Dermatology. SM J Clin. Med. Imaging. 2015, 1(1):1001.
  9. A.Dubnika, D.Loca, I.Salma, A.Reinis, L.Poca, L.Berzina-Cimdina. Evaluation of physical and antimicrobial properties of silver doped hydroxyapatite depending on the preparation method. Journal of Materials Science: Materials in Medicine. 2014, 25(2), 435-444.
  10. A.Dubnika, V.Zalite. Preparation and characterization of porous Ag doped hydroxyapatite bioceramic scaffolds. Ceramics International. 2014, 40(7), Part A, 9923-9930.
  11. L.Poca, A.Dubnika, D.Loca, L.Berzina-Cimdina. Evaluation of silver doped hydroxyapatite scaffold bioactivity in simulated body fluids. Key Engineering Materials. 2014, 604, 175-179.
  12. A.Dubnika, V.Rudovica. Evaluation of silver ion bioavailability from silver doped hydroxyapatite. Key Engineering Materials. 2014, 604, 200-203.
  13. L.Poca, A.Dubnika, D.Loca and L.Berzina-Cimdina. Evaluation of the bioactivity properties of silver doped hydroxyapatite depending on the preparation method. Journal of International Scientific Publications: Materials, Methods and Technologies, 2014, 8, 612-620.
  14. D.Loca, A.Dubnika, A.Reinis, N.Romancikova. In vitro evaluation of osteoblast cell behavior and antimicrobial properties of biphasic calcium phoshpate ceramics. Springer, IFMBE Proceedings. 2013, 38, 186-189.
  15. A.Dubnika, D.Loca, A.Reinis, M.Kodols, L.Berzina-Cimdina. Impact of sintering temperature on the phase composition and antibacterial properties of silver doped hydroxyapatite. Pure and Applied Chemistry. 2013, 85(2), 453-462.
  16. A.Dubnika, D.Loca, L.Berzina-Cimdina. Functionalized hydroxyapatite scaffolds coated with sodium alginate and chitosan for controlled drug delivery. Proceedings of the Estonian Academy of Sciences, 2012, 61(3),193-199.
  17. A.Dubnika, K.Veldre, A.Actins and J.Lescenko. Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates. The Open Conference Proceedings Journal, 2011, 2, 21-27.